Biomarker Services
Molecular Biology
- Genotyping (SNPs)
- Genomic and Plasmid DNA Isolation
- miRNA and mRNA Profiling
- Primer Efficiency
- Protein Expression Systems
- RNA Isolation
- siRNA
- qRT-PCR*
Cell Based or Cell Line Assays
- Bioenergetics and Mitochondrial Targets
- Cell Adhesion
- Collagen Gel Contraction
- Halo (thrombolysis) Assay
- Matrigel Invasion
- Microfluidic or Parallel Plate Flow Chamber
- Motility
- MMPs and TIMPs
- Phenotyping
- Signal Transduction
- Viability, Proliferation, Cytotoxicity, Apoptosis
Protein Chemistry
- Antibody Conjugation
- Enzyme Kinetics
- Individual and Complex Immunoprecipitation
- Protein Biotinylation
- Protein Screening and Quantification
- SDS-PAGE and Western Blot
- Whole cell/Cytosolic/Nuclear Lysate Preparation
ELISA and Multiplex Testing
- Antibody Isotyping (IgA, IgG, IgE)
- Anti-drug Antibodies
- Assay Development, Qualification, and Validation
- Biosimilars
- Cellular Proteins
- Interference Assays
- Protein Quantification
- Screening Assays
- Signaling Pathway Analysis
- Soluble Biomarkers and Biomarker Panels (e.g., cytokines, GF, CAMS, selectins, IL 1-33, GM-CSF,
IFN-g)
Cell Culture
- Gene Silencing
- Generation of Stably Transfected Cell Lines
- Immortalized Cell Culture
- Immunofluorescence
- Maintenance of Frozen Cell Culture Stocks
- Microscopy
- Plasmid DNA Transfection
- Primary Cell Culture
Flow Cytometry/Spectral Flow Cytometry
- Cell Cycle/Proliferation/Apoptosis
- Cell Signaling
- Circulating Endothelial Cells
- Conjugated Antibody Preparation and Detection
- Detection of Cell Surface Proteins
- Immunophenotyping
- Ligand or Antibody Binding; Receptor Occupancy
- Mammalian Cell and Cell-line Antigen/Receptor Analysis
- Microparticles
- Phosphoprotein Detection including VASP*
- Platelet Antigens and Signaling *
- Platelet-Leukocyte Aggregates
- Primary/Secondary Antibody Preparation and Detection
- Reticulocytes
- Whole Blood Cell Analysis (RBC, Platelets, WBC)
Medical Device
- Biocompatibility
- Cell Adhesion (Primary or Tissue Culture)
- Coagulation (Thrombin Generation, TAT, aPTT, PT, etc.)
- Complement Activation (e.g., C3a and 5Cb-9)
- Cytokine Release
- Cytotoxicity
- Drug elution (levels, activity)
- Hemocompatibility (e.g., ASTM 2888-19**)
- Hemolysis (Hgb ELISA)
- Platelet Activation and Adhesion
- Soluble and Cellular Biomarkers*
* FDA compliant validated tests ** Client-directed validated tests *** Qualified 3rd party vendor